pH (low) insertion peptide (pHLIP) targets ischemic myocardium

The pH (low) insertion peptide (pHLIP) family enables targeting of cells in tissues with low extracellular pH. Here, we show that ischemic myocardium is targeted, potentially opening a new route to diagnosis and therapy. The experiments were performed using two murine ischemia models: regional ische...

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Autors principals: Sosunov, Eugene A., Anyukhovsky, Evgeny P., Sosunov, Alexander A., Moshnikova, Anna, Wijesinghe, Dayanjali, Engelman, Donald M., Reshetnyak, Yana K., Andreev, Oleg A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538213/
https://ncbi.nlm.nih.gov/pubmed/23248283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220038110
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