pH (low) insertion peptide (pHLIP) targets ischemic myocardium

The pH (low) insertion peptide (pHLIP) family enables targeting of cells in tissues with low extracellular pH. Here, we show that ischemic myocardium is targeted, potentially opening a new route to diagnosis and therapy. The experiments were performed using two murine ischemia models: regional ische...

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Bibliografiske detaljer
Main Authors: Sosunov, Eugene A., Anyukhovsky, Evgeny P., Sosunov, Alexander A., Moshnikova, Anna, Wijesinghe, Dayanjali, Engelman, Donald M., Reshetnyak, Yana K., Andreev, Oleg A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538213/
https://ncbi.nlm.nih.gov/pubmed/23248283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220038110
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