Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate

Membrane-assisted amyloid formation is implicated in human diseases, and many of the aggregating species accelerate amyloid formation and induce cell death. While structures of membrane-associated intermediates would provide tremendous insights into the pathology and aid in the design of compounds t...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Rodriguez Camargo, Diana C, Korshavn, Kyle J, Jussupow, Alexander, Raltchev, Kolio, Goricanec, David, Fleisch, Markus, Sarkar, Riddhiman, Xue, Kai, Aichler, Michaela, Mettenleiter, Gabriele, Walch, Axel Karl, Camilloni, Carlo, Hagn, Franz, Reif, Bernd, Ramamoorthy, Ayyalusamy
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Biochemistry and Chemical Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706959/
https://ncbi.nlm.nih.gov/pubmed/29148426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31226
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