Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate

Membrane-assisted amyloid formation is implicated in human diseases, and many of the aggregating species accelerate amyloid formation and induce cell death. While structures of membrane-associated intermediates would provide tremendous insights into the pathology and aid in the design of compounds t...

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Опубликовано в: :eLife
Главные авторы: Rodriguez Camargo, Diana C, Korshavn, Kyle J, Jussupow, Alexander, Raltchev, Kolio, Goricanec, David, Fleisch, Markus, Sarkar, Riddhiman, Xue, Kai, Aichler, Michaela, Mettenleiter, Gabriele, Walch, Axel Karl, Camilloni, Carlo, Hagn, Franz, Reif, Bernd, Ramamoorthy, Ayyalusamy
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2017
Предметы:
Biochemistry and Chemical Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706959/
https://ncbi.nlm.nih.gov/pubmed/29148426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31226
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