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Influence of a Curcumin Derivative on hIAPP Aggregation in the Absence and Presence of Lipid Membranes

The deposition of aggregates of human islet amyloid polypeptide (hIAPP) has been correlated with the death of β-cells in type II diabetes mellitus. The actual molecular mechanism of cell death remains largely unknown; however, it has been postulated that the process of aggregation from monomeric hIA...

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Библиографические подробности
Опубликовано в: :Chem Commun (Camb)
Главные авторы: Pithadia, Amit S., Bhunia, Anirban, Sribalan, Rajendran, Padmini, Vediappen, Fierke, Carol A., Ramamoorthy, Ayyalusamy
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703533/
https://ncbi.nlm.nih.gov/pubmed/26587568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc07792c
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