Genome-scale Activation Screen Identifies a LncRNA Locus that Regulates a Gene Neighborhood

The mammalian genome contains thousands of loci that transcribe long noncoding RNAs (lncRNAs)(1-3), some of which are known to play critical roles in diverse cellular processes(4-7). LncRNA loci can contribute to cellular regulation through a variety of mechanisms: while some encode RNAs that act no...

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Publicado no:Nature
Main Authors: Joung, Julia, Engreitz, Jesse M., Konermann, Silvana, Abudayyeh, Omar O., Verdine, Vanessa K., Aguet, Francois, Gootenberg, Jonathan S., Sanjana, Neville E., Wright, Jason B., Fulco, Charles P., Tseng, Yuen-Yi, Yoon, Charles H., Boehm, Jesse S., Lander, Eric S., Zhang, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706657/
https://ncbi.nlm.nih.gov/pubmed/28792927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23451
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