The Xist lncRNA exploits three-dimensional genome architecture to spread across the X-chromosome

Many large noncoding RNAs (lncRNAs) regulate chromatin, but the mechanisms by which they localize to genomic targets remain unexplored. Here we investigate the localization mechanisms of the Xist lncRNA during X-chromosome inactivation (XCI), a paradigm of lncRNA-mediated chromatin regulation. Durin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Engreitz, Jesse M., Pandya-Jones, Amy, McDonel, Patrick, Shishkin, Alexander, Sirokman, Klara, Surka, Christine, Kadri, Sabah, Xing, Jeffrey, Goren, Alon, Lander, Eric S., Plath, Kathrin, Guttman, Mitchell
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778663/
https://ncbi.nlm.nih.gov/pubmed/23828888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237973
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