The Xist lncRNA exploits three-dimensional genome architecture to spread across the X-chromosome

Many large noncoding RNAs (lncRNAs) regulate chromatin, but the mechanisms by which they localize to genomic targets remain unexplored. Here we investigate the localization mechanisms of the Xist lncRNA during X-chromosome inactivation (XCI), a paradigm of lncRNA-mediated chromatin regulation. Durin...

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Библиографические подробности
Главные авторы: Engreitz, Jesse M., Pandya-Jones, Amy, McDonel, Patrick, Shishkin, Alexander, Sirokman, Klara, Surka, Christine, Kadri, Sabah, Xing, Jeffrey, Goren, Alon, Lander, Eric S., Plath, Kathrin, Guttman, Mitchell
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778663/
https://ncbi.nlm.nih.gov/pubmed/23828888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237973
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