The Xist lncRNA exploits three-dimensional genome architecture to spread across the X-chromosome

Many large noncoding RNAs (lncRNAs) regulate chromatin, but the mechanisms by which they localize to genomic targets remain unexplored. Here we investigate the localization mechanisms of the Xist lncRNA during X-chromosome inactivation (XCI), a paradigm of lncRNA-mediated chromatin regulation. Durin...

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Detaylı Bibliyografya
Asıl Yazarlar: Engreitz, Jesse M., Pandya-Jones, Amy, McDonel, Patrick, Shishkin, Alexander, Sirokman, Klara, Surka, Christine, Kadri, Sabah, Xing, Jeffrey, Goren, Alon, Lander, Eric S., Plath, Kathrin, Guttman, Mitchell
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778663/
https://ncbi.nlm.nih.gov/pubmed/23828888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237973
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