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Local regulation of gene expression by lncRNA promoters, transcription, and splicing

Mammalian genomes are pervasively transcribed(1,2) to produce thousands of long noncoding RNAs (lncRNAs)(3,4). A few of these lncRNAs have been shown to recruit regulatory complexes through RNA-protein interactions to influence the expression of nearby genes(5–7), and it has been suggested that many...

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Библиографические подробности
Опубликовано в: :Nature
Главные авторы: Engreitz, Jesse M., Haines, Jenna E., Perez, Elizabeth M., Munson, Glen, Chen, Jenny, Kane, Michael, McDonel, Patrick E., Guttman, Mitchell, Lander, Eric S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853796/
https://ncbi.nlm.nih.gov/pubmed/27783602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20149
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