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Re‐evaluating the foundations of lncRNA–Polycomb function

Many lncRNAs are thought to interact with the polycomb repressive complex 2 (PRC2) in order to regulate gene expression. A central example of this lncRNA–PRC2 paradigm in gene regulation is HOTAIR. In this issue of The EMBO Journal, a study (Portoso et al, 2017) reports that while HOTAIR binds PRC2...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Blanco, Mario R, Guttman, Mitchell
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391134/
https://ncbi.nlm.nih.gov/pubmed/28298433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796796
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