Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice

BACKGROUND: (Over-)expression of arginase may limit local availability of arginine for nitric oxide synthesis. We investigated the significance of arginase1 (ARG1) for the development of airway hyperresponsiveness (AHR) and lung inflammation in female mice with ovalbumin (OVA)-induced allergic asthm...

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Xehetasun bibliografikoak
Argitaratua izan da:BMC Pulm Med
Egile Nagusiak: Cloots, Roy H. E., Sankaranarayanan, Selvakumari, Poynter, Matthew E., Terwindt, Els, van Dijk, Paul, Lamers, Wouter H., Eleonore Köhler, S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706166/
https://ncbi.nlm.nih.gov/pubmed/29183288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-017-0490-7
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