Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice

BACKGROUND: (Over-)expression of arginase may limit local availability of arginine for nitric oxide synthesis. We investigated the significance of arginase1 (ARG1) for the development of airway hyperresponsiveness (AHR) and lung inflammation in female mice with ovalbumin (OVA)-induced allergic asthm...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:BMC Pulm Med
Auteurs principaux: Cloots, Roy H. E., Sankaranarayanan, Selvakumari, Poynter, Matthew E., Terwindt, Els, van Dijk, Paul, Lamers, Wouter H., Eleonore Köhler, S.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706166/
https://ncbi.nlm.nih.gov/pubmed/29183288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-017-0490-7
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires