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Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma
BACKGROUND: Asthma is a chronic respiratory condition, with airway hyperresponsiveness (AHR) and inflammation as hallmarks. The hypothesis that the substantially increased expression of arginase 1 in activated macrophages limits the availability of L-arginine for nitric oxide synthesis, and thus inc...
Gespeichert in:
| Veröffentlicht in: | Respir Res |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5967058/ https://ncbi.nlm.nih.gov/pubmed/29792217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0809-9 |
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