Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice

BACKGROUND: (Over-)expression of arginase may limit local availability of arginine for nitric oxide synthesis. We investigated the significance of arginase1 (ARG1) for the development of airway hyperresponsiveness (AHR) and lung inflammation in female mice with ovalbumin (OVA)-induced allergic asthm...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Cloots, Roy H. E., Sankaranarayanan, Selvakumari, Poynter, Matthew E., Terwindt, Els, van Dijk, Paul, Lamers, Wouter H., Eleonore Köhler, S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706166/
https://ncbi.nlm.nih.gov/pubmed/29183288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-017-0490-7
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