Hepatic Adaptation Compensates Inactivation of Intestinal Arginine Biosynthesis in Suckling Mice

Suckling mammals, including mice, differ from adults in the abundant expression of enzymes that synthesize arginine from citrulline in their enterocytes. To investigate the importance of the small-intestinal arginine synthesis for whole-body arginine production in suckling mice, we floxed exon 13 of...

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Main Authors: Marion, Vincent, Sankaranarayanan, Selvakumari, de Theije, Chiel, van Dijk, Paul, Hakvoort, Theo B. M., Lamers, Wouter H., Köhler, Eleonore S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681768/
https://ncbi.nlm.nih.gov/pubmed/23785515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067021
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