ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα

The transcription factor C/EBPα is essential for myeloid differentiation and is frequently dysregulated in acute myeloid leukemia. Although studied extensively, the precise regulation of its gene by upstream factors has remained largely elusive. Here, we investigated its transcriptional activation d...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Gonzalez, David, Luyten, Annouck, Bartholdy, Boris, Zhou, Qiling, Kardosova, Miroslava, Ebralidze, Alex, Swanson, Kenneth D., Radomska, Hanna S., Zhang, Pu, Kobayashi, Susumu S., Welner, Robert S., Levantini, Elena, Steidl, Ulrich, Chong, Gilbert, Collombet, Samuel, Choi, Min Hee, Friedman, Alan D., Scott, Linda M., Alberich-Jorda, Meritxell, Tenen, Daniel G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704476/
https://ncbi.nlm.nih.gov/pubmed/28900037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811109
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