C/EBPα Induces PU.1 and Interacts with AP-1 and NF-κB to Regulate Myeloid Development

di Friedman, Alan D.
Pubblicazione 2007

C/EBPα in normal and malignant myelopoiesis

di Friedman, Alan D.
Pubblicato in Int J Hematol (2015)

Cell Cycle and Developmental Control of Hematopoiesis by Runx1

di Friedman, Alan D.
Pubblicato in J Cell Physiol (2009)

Phosphorylation of RUNX1 by Cyclin-dependent Kinase Reduces Direct Interaction with HDAC1 and HDAC3

di Guo, Hong, Friedman, Alan D.
Pubblicazione 2011

SHP2 tyrosine phosphatase stimulates CEBPA gene expression to mediate cytokine-dependent granulopoiesis

di Zhang, Li, Friedman, Alan D.
Pubblicazione 2011

C/EBPα Dysregulation in AML and ALL

di Paz-Priel, Ido, Friedman, Alan D.
Pubblicazione 2011

Multimerization via Its Myosin Domain Facilitates Nuclear Localization and Inhibition of Core Binding Factor (CBF) Activities by the CBFβ-Smooth Muscle Myosin Heavy Chain Myeloid L...

di Kummalue, Tanawan, Lou, Jianrong, Friedman, Alan D.
Pubblicazione 2002

The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells

di Guo, Hong, Ma, Ou, Friedman, Alan D.
Pubblicazione 2014

The +37 kb Cebpa Enhancer Is Critical for Cebpa Myeloid Gene Expression and Contains Functional Sites that Bind SCL, GATA2, C/EBPα, PU.1, and Additional Ets Factors

di Cooper, Stacy, Guo, Hong, Friedman, Alan D.
Pubblicato in PLoS One (2015)

In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis

di Guo, Hong, Cooper, Stacy, Friedman, Alan D.
Pubblicato in PLoS One (2016)

C/EBPα induces Ebf1 gene expression in common lymphoid progenitors

di Barberi, Theresa, Cui, Cheng, Friedman, Alan D.
Pubblicato in PLoS One (2020)

NF-κB p50 Regulates C/EBPα Expression and Inflammatory Cytokine-Induced Neutrophil Production

di Wang, Dehua, Paz-Priel, Ido, Friedman, Alan D.
Pubblicazione 2009

M-CSF elevates c-Fos and phospho-C/EBPα(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification

di Jack, Graham D., Zhang, Li, Friedman, Alan D.
Pubblicazione 2009

Progression from the Common Lymphoid Progenitor to B/Myeloid preproB and proB Precursors During B Lymphopoiesis Requires C/EBPα

di Guo, Hong, Barberi, Theresa, Suresh, Rahul, Friedman, Alan D.
Pubblicato in J Immunol (2018)

Adoptive transfer of immature myeloid cells lacking NF‐κB p50 (p50‐IMC) impedes the growth of MHC‐matched high‐risk neuroblastoma

di Cui, Cheng, Barberi, Theresa, Suresh, Rahul, Friedman, Alan D.
Pubblicato in Mol Oncol (2021)

Cyclin-dependent kinase phosphorylation of RUNX1/AML1 on 3 sites increases transactivation potency and stimulates cell proliferation

di Zhang, Linsheng, Fried, Florence B., Guo, Hong, Friedman, Alan D.
Pubblicazione 2008

C/EBPα and C/EBPα oncoproteins regulate nfkb1 and displace histone deacetylases from NF-κB p50 homodimers to induce NF-κB target genes

di Paz-Priel, Ido, Houng, Simone, Dooher, Julia, Friedman, Alan D.
Pubblicazione 2011

Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis

di Guo, Hong, Ma, Ou, Speck, Nancy A., Friedman, Alan D.
Pubblicazione 2012

C/EBPα directs monocytic commitment of primary myeloid progenitors

di Wang, Dehua, D'Costa, Jenice, Civin, Curt I., Friedman, Alan D.
Pubblicazione 2006

AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription

di Hong, SunHwa, Skaist, Alyza M., Wheelan, Sarah J., Friedman, Alan D.
Pubblicazione 2011