Caricamento...

The +37 kb Cebpa Enhancer Is Critical for Cebpa Myeloid Gene Expression and Contains Functional Sites that Bind SCL, GATA2, C/EBPα, PU.1, and Additional Ets Factors

The murine Cebpa gene contains an evolutionarily conserved 453 bp enhancer located at +37 kb that, together with its promoter, directs expression to myeloid progenitors and to long-term hematopoietic stem cells in transgenic mice. In human acute myeloid leukemia cases, the enhancer lacks point mutat...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Cooper, Stacy, Guo, Hong, Friedman, Alan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418761/
https://ncbi.nlm.nih.gov/pubmed/25938608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126385
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !