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Regulation of human and mouse telomerase genes by genomic contexts and transcription factors during embryonic stem cell differentiation

Differential regulation of telomerase reverse transcriptase (TERT) genes contribute to distinct aging and tumorigenic processes in humans and mice. To study TERT regulation, we generated mouse embryonic stem cell (ESC) lines containing single-copy bacterial artificial chromosome (BAC) reporters, cov...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cheng, De, Wang, Shuwen, Jia, Wenwen, Zhao, Yuanjun, Zhang, Fan, Kang, Jiuhong, Zhu, Jiyue
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703907/
https://ncbi.nlm.nih.gov/pubmed/29180668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16764-w
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