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Regulation of human and mouse telomerase genes by genomic contexts and transcription factors during embryonic stem cell differentiation

Differential regulation of telomerase reverse transcriptase (TERT) genes contribute to distinct aging and tumorigenic processes in humans and mice. To study TERT regulation, we generated mouse embryonic stem cell (ESC) lines containing single-copy bacterial artificial chromosome (BAC) reporters, cov...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Cheng, De, Wang, Shuwen, Jia, Wenwen, Zhao, Yuanjun, Zhang, Fan, Kang, Jiuhong, Zhu, Jiyue
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703907/
https://ncbi.nlm.nih.gov/pubmed/29180668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16764-w
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