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Transcriptional Silencing of a Novel hTERT Reporter Locus during In Vitro Differentiation of Mouse Embryonic Stem Cells

The human telomerase reverse transcriptase hTERT is highly expressed in undifferentiated embryonic cells and silenced in the majority of somatic cells. To investigate the mechanisms of hTERT silencing, we have developed a novel reporter using a bacterial artificial chromosome (BAC) that contained th...

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Detalhes bibliográficos
Main Authors: Wang, Shuwen, Hu, Chunguang, Zhu, Jiyue
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783791/
https://ncbi.nlm.nih.gov/pubmed/17151355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0840
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