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Transcriptional Silencing of a Novel hTERT Reporter Locus during In Vitro Differentiation of Mouse Embryonic Stem Cells

The human telomerase reverse transcriptase hTERT is highly expressed in undifferentiated embryonic cells and silenced in the majority of somatic cells. To investigate the mechanisms of hTERT silencing, we have developed a novel reporter using a bacterial artificial chromosome (BAC) that contained th...

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Hlavní autoři: Wang, Shuwen, Hu, Chunguang, Zhu, Jiyue
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783791/
https://ncbi.nlm.nih.gov/pubmed/17151355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0840
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