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Rearrangement of Upstream Sequences of the hTERT Gene During Cellular Immortalization

Telomerase expression, resulting from transcriptional activation of the hTERT gene, allows cells to acquire indefinite proliferative potential during cellular immortalization and tumorigenesis. However, mechanisms of hTERT gene activation in many immortal cell lines and cancer cells are poorly under...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Yuanjun, Wang, Shuwen, Popova, Evgenya Y., Grigoryev, Sergei A., Zhu, Jiyue
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889911/
https://ncbi.nlm.nih.gov/pubmed/19672873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20698
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