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Rearrangement of Upstream Sequences of the hTERT Gene During Cellular Immortalization

Telomerase expression, resulting from transcriptional activation of the hTERT gene, allows cells to acquire indefinite proliferative potential during cellular immortalization and tumorigenesis. However, mechanisms of hTERT gene activation in many immortal cell lines and cancer cells are poorly under...

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Detalhes bibliográficos
Main Authors: Zhao, Yuanjun, Wang, Shuwen, Popova, Evgenya Y., Grigoryev, Sergei A., Zhu, Jiyue
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889911/
https://ncbi.nlm.nih.gov/pubmed/19672873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20698
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