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The intrabody targeting of hTERT attenuates the immortality of cancer cells

hTERT (human telomerase reverse transcriptase) plays a key role in the process of cell immortalization. Overexpression of hTERT has been implicated in 85% of malignant tumors and offers a specific target for cancer therapy. In this paper, we describe an effective approach using a single-chain variab...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Zhu, Xiangying, Yang, Nan, Cai, Jianguo, Yang, Guimei, Liang, Shenghua, Ren, Daming
Formato: Artigo
Idioma:Inglês
Publicado em: SP Versita 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275974/
https://ncbi.nlm.nih.gov/pubmed/19774346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-009-0032-2
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