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The intrabody targeting of hTERT attenuates the immortality of cancer cells
hTERT (human telomerase reverse transcriptase) plays a key role in the process of cell immortalization. Overexpression of hTERT has been implicated in 85% of malignant tumors and offers a specific target for cancer therapy. In this paper, we describe an effective approach using a single-chain variab...
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| Publicat a: | Cell Mol Biol Lett |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SP Versita
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6275974/ https://ncbi.nlm.nih.gov/pubmed/19774346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-009-0032-2 |
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