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Regulation of human and mouse telomerase genes by genomic contexts and transcription factors during embryonic stem cell differentiation
Differential regulation of telomerase reverse transcriptase (TERT) genes contribute to distinct aging and tumorigenic processes in humans and mice. To study TERT regulation, we generated mouse embryonic stem cell (ESC) lines containing single-copy bacterial artificial chromosome (BAC) reporters, cov...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703907/ https://ncbi.nlm.nih.gov/pubmed/29180668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16764-w |
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