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Prediction of antibody structural epitopes via random peptide library screening and next generation sequencing
Next generation sequencing (NGS) is widely applied in immunological research, but has yet to become common in antibody epitope mapping. A method utilizing a 12-mer random peptide library expressed in bacteria coupled with magnetic-based cell sorting and NGS correctly identified more than 75% of epit...
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| Pubblicato in: | J Immunol Methods |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698135/ https://ncbi.nlm.nih.gov/pubmed/28827189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2017.08.004 |
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