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Genetically tunable frustration controls allostery in an intrinsically disordered transcription factor
Intrinsically disordered proteins (IDPs) present a functional paradox because they lack stable tertiary structure, but nonetheless play a central role in signaling, utilizing a process known as allostery. Historically, allostery in structured proteins has been interpreted in terms of propagated stru...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5697930/ https://ncbi.nlm.nih.gov/pubmed/29022880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30688 |
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