Dynamic allostery can drive cold adaptation in enzymes

Por Saavedra, Harry G., Wrabl, James O., Anderson, Jeremy A., Li, Jing, Hilser, Vincent J.
Publicado no Nature (2018)

Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform

Por Shumar, Stephanie A., Kerr, Evan W., Geldenhuys, Werner J., Montgomery, Grace E., Fagone, Paolo, Thirawatananond, Puchong, Saavedra, Harry, Gabelli, Sandra B., Leonardi, Roberta
Publicado no J Biol Chem (2018)

Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt(Mt2) by biapenem and tebipenem

Por Bianchet, Mario A., Pan, Ying H., Basta, Leighanne A. Brammer, Saavedra, Harry, Lloyd, Evan P., Kumar, Pankaj, Mattoo, Rohini, Townsend, Craig A., Lamichhane, Gyanu
Publicado no BMC Biochem (2017)

Genetically tunable frustration controls allostery in an intrinsically disordered transcription factor

Por Li, Jing, White, Jordan T, Saavedra, Harry, Wrabl, James O, Motlagh, Hesam N, Liu, Kaixian, Sowers, James, Schroer, Trina A, Thompson, E Brad, Hilser, Vincent J
Publicado no eLife (2017)

Correction: Genetically tunable frustration controls allostery in an intrinsically disordered transcription factor

Por Li, Jing, White, Jordan T, Saavedra, Harry, Wrabl, James O, Motlagh, Hesam N, Liu, Kaixian, Sowers, James, Schroer, Trina A, Thompson, E Brad, Hilser, Vincent J
Publicado no eLife (2018)