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Ensemble allosteric model: energetic frustration within the intrinsically disordered glucocorticoid receptor

Allostery is an important regulatory phenomenon enabling precise control of biological function. Initial understanding of allostery was gained from seminal work on conformational changes exhibited by structured proteins. Within the last decade, protein allostery has also been demonstrated to occur w...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: White, Jordan T., Li, Jing, Grasso, Emily, Wrabl, James O., Hilser, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941170/
https://ncbi.nlm.nih.gov/pubmed/29735729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0175
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