Loading...

Granzyme B disrupts central metabolism and protein synthesis in bacteria to promote an immune cell death program

Human cytotoxic lymphocytes kill intracellular microbes. The cytotoxic granule granzyme proteases released by cytotoxic lymphocytes trigger oxidative bacterial death by disrupting electron transport, generating superoxide anion and inactivating bacterial oxidative defenses. However, they also cause...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Dotiwala, Farokh, Santara, Sumit Sen, Binker-Cosen, Andres Ariel, Li, Bo, Chandrasekaran, Sriram, Lieberman, Judy
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693722/
https://ncbi.nlm.nih.gov/pubmed/29107333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.10.004
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!