Loading...

Cytotoxic cells kill intracellular bacteria through Granulysin-mediated delivery of Granzymes

When killer lymphocytes recognize infected cells, perforin delivers cytotoxic proteases (granzymes) into the target cell to trigger apoptosis. What happens to intracellular bacteria during this process is unclear. Human, but not rodent, cytotoxic granules also contain granulysin, an antimicrobial pe...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Walch, Michael, Dotiwala, Farokh, Mulik, Sachin, Thiery, Jerome, Kirchhausen, Tomas, Clayberger, Carol, Krensky, Alan M., Martinvalet, Denis, Lieberman, Judy
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090916/
https://ncbi.nlm.nih.gov/pubmed/24906149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.062
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!