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Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites
Protozoan infections are a serious global health problem(1,2). Natural killer (NK) cells and cytolytic T lymphocytes (CTLs) eliminate pathogen-infected cells by releasing cytolytic granule contents—granzyme (Gzm) proteases and the pore-forming perforin (PFN)—into the infected cell(3). However, these...
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| Publicado en: | Nat Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7325279/ https://ncbi.nlm.nih.gov/pubmed/26752517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4023 |
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