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A High Yield and Cost-efficient Expression System of Human Granzymes in Mammalian Cells

When cytotoxic T lymphocytes (CTL) or natural killer (NK) cells recognize tumor cells or cells infected with intracellular pathogens, they release their cytotoxic granule content to eliminate the target cells and the intracellular pathogen. Death of the host cells and intracellular pathogens is trig...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Dotiwala, Farokh, Fellay, Isabelle, Filgueira, Luis, Martinvalet, Denis, Lieberman, Judy, Walch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544413/
https://ncbi.nlm.nih.gov/pubmed/26132420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52911
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