A High Yield and Cost-efficient Expression System of Human Granzymes in Mammalian Cells

When cytotoxic T lymphocytes (CTL) or natural killer (NK) cells recognize tumor cells or cells infected with intracellular pathogens, they release their cytotoxic granule content to eliminate the target cells and the intracellular pathogen. Death of the host cells and intracellular pathogens is trig...

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Vydáno v:J Vis Exp
Hlavní autoři: Dotiwala, Farokh, Fellay, Isabelle, Filgueira, Luis, Martinvalet, Denis, Lieberman, Judy, Walch, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2015
Témata:
Biochemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544413/
https://ncbi.nlm.nih.gov/pubmed/26132420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52911
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