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Granzyme B Attenuates Bacterial Virulence by Targeting Secreted Factors

Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here we show t...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: León, Diego López, Matthey, Patricia, Fellay, Isabelle, Blanchard, Marianne, Martinvalet, Denis, Mantel, Pierre-Yves, Filgueira, Luis, Walch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063247/
https://ncbi.nlm.nih.gov/pubmed/32151975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100932
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