Granzyme B Attenuates Bacterial Virulence by Targeting Secreted Factors

Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here we show t...

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Bibliographic Details
Published in:iScience
Main Authors: León, Diego López, Matthey, Patricia, Fellay, Isabelle, Blanchard, Marianne, Martinvalet, Denis, Mantel, Pierre-Yves, Filgueira, Luis, Walch, Michael
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063247/
https://ncbi.nlm.nih.gov/pubmed/32151975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100932
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