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Cytotoxic cells kill intracellular bacteria through Granulysin-mediated delivery of Granzymes
When killer lymphocytes recognize infected cells, perforin delivers cytotoxic proteases (granzymes) into the target cell to trigger apoptosis. What happens to intracellular bacteria during this process is unclear. Human, but not rodent, cytotoxic granules also contain granulysin, an antimicrobial pe...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090916/ https://ncbi.nlm.nih.gov/pubmed/24906149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.062 |
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