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Death by a Thousand Cuts: Granzyme Pathways of Programmed Cell Death
The granzymes are cell death–inducing enzymes, stored in the cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, that are released during granule exocytosis when a specific virus-infected or transformed target cell is marked for elimination. Recent work suggests that this homolog...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790083/ https://ncbi.nlm.nih.gov/pubmed/18304003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.immunol.26.021607.090404 |
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