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Death by a Thousand Cuts: Granzyme Pathways of Programmed Cell Death

The granzymes are cell death–inducing enzymes, stored in the cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, that are released during granule exocytosis when a specific virus-infected or transformed target cell is marked for elimination. Recent work suggests that this homolog...

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Detalhes bibliográficos
Main Authors: Chowdhury, Dipanjan, Lieberman, Judy
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790083/
https://ncbi.nlm.nih.gov/pubmed/18304003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.immunol.26.021607.090404
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