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DRES-06. PRIMARY RESISTANCE TO EGFR INHIBITION IN GLIOBLASTOMA IS MEDIATED BY A TNF-JNK-Axl-ERK SIGNALING AXIS
Aberrant EGFR signaling is widespread in various forms of cancer, but EGFR inhibition seems to be primarily effective only in a subset of lung cancers that harbor EGFR activating mutations and are oncogene addicted. Most cancers with aberrant EGFR signaling are not oncogene addicted and exhibit a pr...
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| 出版年: | Neuro Oncol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693050/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.264 |
| タグ: |
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