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DRES-06. PRIMARY RESISTANCE TO EGFR INHIBITION IN GLIOBLASTOMA IS MEDIATED BY A TNF-JNK-Axl-ERK SIGNALING AXIS

Aberrant EGFR signaling is widespread in various forms of cancer, but EGFR inhibition seems to be primarily effective only in a subset of lung cancers that harbor EGFR activating mutations and are oncogene addicted. Most cancers with aberrant EGFR signaling are not oncogene addicted and exhibit a pr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuro Oncol
मुख्य लेखकों: Guo, Gao, Gong, Ke, Habib, Amyn
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693050/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.264
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