Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary malignant adult brain tumor. Temozolomide (TMZ) is the standard of care and is most effective in GBMs that lack the DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT). Moreover, even initially responsive tumors develop a secon...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Guo, Gao, Gong, Ke, Puliyappadamba, Vineshkumar Thidil, Panchani, Nishah, Pan, Edward, Mukherjee, Bipasha, Damanwalla, Ziba, Bharia, Sabrina, Hatanpaa, Kimmo J, Gerber, David E, Mickey, Bruce E, Patel, Toral R, Sarkaria, Jann N, Zhao, Dawen, Burma, Sandeep, Habib, Amyn A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917414/
https://ncbi.nlm.nih.gov/pubmed/31363754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz127
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