Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary malignant adult brain tumor. Temozolomide (TMZ) is the standard of care and is most effective in GBMs that lack the DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT). Moreover, even initially responsive tumors develop a secon...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Guo, Gao, Gong, Ke, Puliyappadamba, Vineshkumar Thidil, Panchani, Nishah, Pan, Edward, Mukherjee, Bipasha, Damanwalla, Ziba, Bharia, Sabrina, Hatanpaa, Kimmo J, Gerber, David E, Mickey, Bruce E, Patel, Toral R, Sarkaria, Jann N, Zhao, Dawen, Burma, Sandeep, Habib, Amyn A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Basic and Translational Investigations
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917414/
https://ncbi.nlm.nih.gov/pubmed/31363754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz127
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