Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary malignant adult brain tumor. Temozolomide (TMZ) is the standard of care and is most effective in GBMs that lack the DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT). Moreover, even initially responsive tumors develop a secon...

詳細記述

保存先:
書誌詳細
出版年:Neuro Oncol
主要な著者: Guo, Gao, Gong, Ke, Puliyappadamba, Vineshkumar Thidil, Panchani, Nishah, Pan, Edward, Mukherjee, Bipasha, Damanwalla, Ziba, Bharia, Sabrina, Hatanpaa, Kimmo J, Gerber, David E, Mickey, Bruce E, Patel, Toral R, Sarkaria, Jann N, Zhao, Dawen, Burma, Sandeep, Habib, Amyn A
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
Basic and Translational Investigations
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917414/
https://ncbi.nlm.nih.gov/pubmed/31363754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz127
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