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Augmented HR Repair Mediates Acquired-temozolomide Resistance in Glioblastoma
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults, and is universally fatal. The DNA alkylating agent temzolomide (TMZ) is part of the standard-of-care for GBM. However, these tumors eventually develop therapy-driven resistance and inevitably recur. While...
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| Publicado no: | Mol Cancer Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065752/ https://ncbi.nlm.nih.gov/pubmed/27358111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0125 |
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