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DRES-01. EFFICACY OF EGFR PLUS TNF INHIBITION IN A PRECLINICAL MODEL OF GLIOBLASTOMA

EGFR gene amplification and mutation are common in glioblastoma (GBM), but EGFR inhibition is not effective in treating this tumor. EGFR inhibition may fail because EGFR is not a driver of the malignant phenotype in GBM, or because adaptive compensatory mechanisms are triggered by EGFR inhibition th...

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Foilsithe in:Neuro Oncol
Main Authors: Guo, Gao, Gong, Ke, Sarkaria, Jann, Habib, Amyn
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847388/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.289
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