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DRES-01. EFFICACY OF EGFR PLUS TNF INHIBITION IN A PRECLINICAL MODEL OF GLIOBLASTOMA

EGFR gene amplification and mutation are common in glioblastoma (GBM), but EGFR inhibition is not effective in treating this tumor. EGFR inhibition may fail because EGFR is not a driver of the malignant phenotype in GBM, or because adaptive compensatory mechanisms are triggered by EGFR inhibition th...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Guo, Gao, Gong, Ke, Sarkaria, Jann, Habib, Amyn
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847388/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.289
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