PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP

Apoptosis and necroptosis are two distinct cell death mechanisms that may be activated in cells on stimulation by TNFα. It is still unclear, however, how apoptosis and necroptosis may be differentially regulated. Here we screened for E3 ubiquitin ligases that could mediate necroptosis. We found that...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wang, Huibing, Meng, Huyan, Li, Xingyan, Zhu, Kezhou, Dong, Kangyun, Mookhtiar, Adnan K., Wei, Huiting, Li, Ying, Sun, Shao-Cong, Yuan, Junying
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692605/
https://ncbi.nlm.nih.gov/pubmed/29078411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715742114
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars