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Parkin regulates NF-κB by mediating site-specific ubiquitination of RIPK1
Parkin (Park2), a RING-between-RING-type E3 ubiquitin ligase, has been implicated in regulating NF-κB. Mutations in Parkin are associated with Parkinson’s disease. Here we investigated the interaction of Parkin with Receptor-interacting protein kinase 1 (RIPK1) kinase, a key mediator of multiple sig...
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| Publié dans: | Cell Death Dis |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6023924/ https://ncbi.nlm.nih.gov/pubmed/29955050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0770-z |
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