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Ubiquitin-mediated NFκB degradation pathway
The nuclear factor κB (NFκB) transcription factor plays critical roles in inflammation and immunity. The dysregulation of NFκB is associated with inflammatory and autoimmune diseases and cancer. NFκB activation is negatively regulated by the ubiquitin-dependent proteasomal degradation pathway. In th...
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| Veröffentlicht in: | Cell Mol Immunol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4716629/ https://ncbi.nlm.nih.gov/pubmed/25345807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.99 |
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