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Ubiquitin-mediated NFκB degradation pathway

The nuclear factor κB (NFκB) transcription factor plays critical roles in inflammation and immunity. The dysregulation of NFκB is associated with inflammatory and autoimmune diseases and cancer. NFκB activation is negatively regulated by the ubiquitin-dependent proteasomal degradation pathway. In th...

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Bibliografiske detaljer
Udgivet i:Cell Mol Immunol
Main Authors: Xu, Huimin, You, Mengli, Shi, Haifeng, Hou, Yongzhong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716629/
https://ncbi.nlm.nih.gov/pubmed/25345807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.99
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