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Ubiquitination and Degradation of the Inhibitors of NF-κB

The key step in NF-κB activation is the release of the NF-κB dimers from their inhibitory proteins, achieved via proteolysis of the IκBs. This irreversible signaling step constitutes a commitment to transcriptional activation. The signal is eventually terminated through nuclear expulsion of NF-κB, t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kanarek, Naama, London, Nir, Schueler-Furman, Ora, Ben-Neriah, Yinon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828279/
https://ncbi.nlm.nih.gov/pubmed/20182612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000166
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