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Ubiquitination and Degradation of the Inhibitors of NF-κB
The key step in NF-κB activation is the release of the NF-κB dimers from their inhibitory proteins, achieved via proteolysis of the IκBs. This irreversible signaling step constitutes a commitment to transcriptional activation. The signal is eventually terminated through nuclear expulsion of NF-κB, t...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828279/ https://ncbi.nlm.nih.gov/pubmed/20182612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000166 |
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