Innate Immune-Directed NF-κB Signaling Requires Site-Specific NEMO Ubiquitination

While the I kappa kinase (IKK) scaffolding protein NF-κB essential modulator (NEMO) binds to polyubiquitin chains to transmit inflammatory signals, NEMO itself is also ubiquitinated in response to a variety of inflammatory agonists. Although there have been hints that polyubiquitination of NEMO is e...

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Bibliografiset tiedot
Päätekijät: Jun, Janice C., Kertesy, Sylvia, Jones, Mark B., Marinis, Jill M., Cobb, Brian A., Tigno-Aranjuez, Justine T., Abbott, Derek W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843603/
https://ncbi.nlm.nih.gov/pubmed/23871670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.036
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