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Innate Immune-Directed NF-κB Signaling Requires Site-Specific NEMO Ubiquitination
While the I kappa kinase (IKK) scaffolding protein NF-κB essential modulator (NEMO) binds to polyubiquitin chains to transmit inflammatory signals, NEMO itself is also ubiquitinated in response to a variety of inflammatory agonists. Although there have been hints that polyubiquitination of NEMO is e...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843603/ https://ncbi.nlm.nih.gov/pubmed/23871670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.036 |
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