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Structural basis of human kinesin-8 function and inhibition

Kinesin motors play diverse roles in mitosis and are targets for antimitotic drugs. The clinical significance of these motors emphasizes the importance of understanding the molecular basis of their function. Equally important, investigations into the modes of inhibition of these motors provide cruci...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Locke, Julia, Joseph, Agnel Praveen, Peña, Alejandro, Möckel, Martin M., Mayer, Thomas U., Topf, Maya, Moores, Carolyn A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692573/
https://ncbi.nlm.nih.gov/pubmed/29078367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712169114
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