Structural basis of human kinesin-8 function and inhibition

Kinesin motors play diverse roles in mitosis and are targets for antimitotic drugs. The clinical significance of these motors emphasizes the importance of understanding the molecular basis of their function. Equally important, investigations into the modes of inhibition of these motors provide cruci...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Locke, Julia, Joseph, Agnel Praveen, Peña, Alejandro, Möckel, Martin M., Mayer, Thomas U., Topf, Maya, Moores, Carolyn A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692573/
https://ncbi.nlm.nih.gov/pubmed/29078367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712169114
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