METB-14. DOWN-REGULATION OF ACETATE METABOLISM TOWARDS FATTY ACIDS IN IDH1 MUTANT GLIOMA

Acetate has recently been identified as a major alternative source of nutrients for glioblastoma and brain metastases. After cellular uptake, acetate is converted to acetyl-CoA, a key metabolic intermediate that fuels the TCA cycle and is an essential building block for the biosynthesis of fatty aci...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Najac, Chloe, Radoul, Marina, Viswanath, Pavithra, Chaumeil, Myriam M, Ronen, Sabrina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692264/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.537
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