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EXTH-76. (1)H AND HYPERPOLARIZED (13)C MRS BIOMARKERS OF IDH1 MUTANT GLIOMA RESPONSE TO TEMOZOLOMIDE THERAPY

The alkylating agent temozolomide (TMZ), previously reserved for treatment of glioblastoma, is now being considered for the treatment of low-grade glioma that are driven by mutations in the isocitrate dehydrogenase 1 (IDH1) gene. Though the treatment of IDH1 mutant patients with TMZ improves surviva...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Subramani, Elavarasan, Najac, Chloe, Batsios, Georgios, Viswanath, Pavithra, Radoul, Marina, Gillespie, Anne Marie, Pieper, Russell, Ronen, Sabrina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216354/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.423
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